Creams for Pain: Can the application of cream at any painful area is free of risk?

Creams for Pain: Can the application of cream at any painful area is free of risk?

Can the application of cream in any painful area is free of risk?

Topical application of NSAID also will be absorbed systemically and can cause gastritis and renal damage. It had been believed that when NSAID is applied topically will act only on that site and will not be absorbed systemically thus no side effects. It has been proved that analgesic action due to topical NSAID is very minimal and most action is due to the placebo effect.

It will be absorbed systemically and will cause gastritis and renal damage, though less intense than oral or systemic NSAID. It can also cause local skin damage and a reaction.